Determination of diazolidinyl urea in cosmetic formulations by capillary electrophoresis
Robert J. Geise , Nancy I. Machnicki , Robert M. Ianniello

Synopsis

Capillary electrophoresis (CE) is demonstrated for the determination of the preservative diazolidinyl urea in cosmetic formulations. The extremely high resolving power of CE separates the compound from other detectable formulation components. This direct method is an improvement over traditionally used methods, which involve derivatization\/degradation reactions. Due to complex matrices, the method of standard additions is used for quantitation. A negative charge is effected by the use of borate buffer (pH 9.3), and diazolidinyl urea elutes at ca. 4 minutes with detection at 215 nm.

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