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© 1979 Society of Cosmetic Chemists
Journal of the Society of Cosmetic Chemists, Vol. 30, No. 4, 181-190


Transepidermal moisture loss III. An in vitro approach
Gene R. Beruhe , Frank Tranner

ABSTRACT

Synopsis

To facilitate OCCLUSIVE SCREENING EVALUATIONS at LOW relative HUMIDITIES, we have developed an IN VITRO model system using a polymeric film to simulate a skin substrate. The apparatus and the control and effects of temperature and relative humidity are described. Examples of the application of this device to the screening of some typical creams and lotions, USP Petrolatum, and some specific raw materials are given. It is shown that the effectiveness of some materials differs with the test humidity.

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© 1979 Society of Cosmetic Chemists
Journal of the Society of Cosmetic Chemists