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© 1974 Society of Cosmetic Chemists
Journal of the Society of Cosmetic Chemists, Vol. 25, No. 5, 283-296


Testing for Inhalation Toxicity
William R. Troy

ABSTRACT

Synopsis

The purpose of this review is to outline some of the fundamental considerations involved in testing for INHALATION SAFETY of COSMETIC PRODUCTS. Apart from design of the exposure system and selection of test animals, factors such as environmental controls, proper dose levels, and signs of TOXICITY to watch for are of prime importance when conducting such studies.

A discussion of three areas of concern with regard to the inhalation safety of cosmetic AEROSOLS is also included. The questions of hair spray “storage disease,” possible aspiration of spray talc, and allegations of cardiotoxicity of aerosol propellants are treated with regard to experimental activity in these areas and what, if anything, has been proven to date by these investigations.

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© 1974 Society of Cosmetic Chemists
Journal of the Society of Cosmetic Chemists