Appraisal of Efficacy of Antidandruff Formulations
Albert M. Kligman , Richard R. Marples , Larry R. Lantis , Kenneth J. McGinley

Synopsis

The EFFECTIVENESS of ANTIDANDRUFF SHAMPOOS and grooming agents can be reliably assessed in a month's time on groups as small as 10 persons. The important prerequisites are that the subjects have at least moderately severe dandruff and that estimations be made at a fixed interval after washing the scalp.

Two modes of EVALUATION are utilized: (a) a subjective one in which the amount of scaling is scored on a 0 to 10 scale, and (b) an objective one in which the quantity of horny cells produced is measured in a hemocytometer. Data are given for two widely used efficacious shampoos and for a nonmedicated control. These are valuable benchmarks which enable products to be compared on a scale of comparative merit.

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