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© 1966 Society of Cosmetic Chemists
Journal of the Society of Cosmetic Chemists, Vol. 17, No. 6, 355-360


Cyclic Salicylanilides as Antibacterial Agents
Winthrop E. Lange , Jon C. Anderson

ABSTRACT

Synopsis

A number of halogen, trifluoromethyl, and sulfur-containing salicylanilides along with cyclic derivatives of these same compounds were prepared for evaluation as antibacterial agents. The effects of structure modification on activity were shown by a densitometric minimum inhibitory concentration technique. The trifluoromethyl-substituted salicylanilides and their cyclic derivatives were found to be the most potent antibacterial agents.

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© 1966 Society of Cosmetic Chemists
Journal of the Society of Cosmetic Chemists